Tadalis SX

Precautions

If you have certain conditions, you may need a dose adjustment or special tests to safely take Tadalis SX (Tadalafil). Before taking this medication, tell your doctor if you are allergic to any drugs, or if you have or have had:

• A heart disease or heart rhythm problems
• Recent history of a heart attack (within the past 90 days)
• Recent history of a stroke or congestive heart failure (within the past 6 months)
• Angina (chest pain)
• High or low blood pressure
• Liver disease
• Kidney disease (or if you are on dialysis)
• A blood cell disorder such as sickle cell anemia, multiple myeloma or leukemia
• A bleeding disorder such as hemophilia
• A stomach ulcer
• Retinitis pigmentosa (an inherited condition of the eye)
• A physical deformity of the penis (such as Peyronie's disease)

 Do not take this medication if you have been told you should not have sexual intercourse for health reasons. Stop using Tadalis SX (Tadalafil) and get emergency medical help if you experience a sudden loss of vision.

Although Tadalis SX (Tadalafil) is not intended for use by women, it is not known if Tadalafil passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are pregnant, plan on becoming pregnant during treatment, or are breast-feeding a baby.

Drug interactions

Before using Tadalis SX (Tadalafil), notify your doctor about other medications you use, especially:

• A nitrate such as nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, Minitran, Deponit, Transderm-Nitro, others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), isosorbide mononitrate (Imdur, ISMO, Monoket) and others
• Nitrates found in some recreational drugs such as amyl nitrate or nitrite ("poppers")
• An alpha blocker (other than tamsulosin (Flomax) 0.4 mg once a day) such as doxazosin (Cardura), guanadrel (Hylorel), prazosin (Minipress), terazosin (Hytrin), alfuzosin (Uroxatral) and others.

Taking this medication with any of these medications may cause very low blood pressure, possibly resulting in dizziness, loss of consciousness, a stroke or a heart attack.

Before taking Tadalis SX (Tadalafil), inform your doctor of all other medications you use for erectile dysfunction, or if you are using any of the following medications:

• Conivaptan (Vaprisol)
• Diclofenac (Arthrotec, Cataflam, Voltaren, Flector Patch, Solareze)
• Doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin)
• Imatinib (Gleevec)
• Isoniazid (for treating tuberculosis)
• Rifampin (Rifadin, Rimactane)
• An antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin) or telithromycin (Ketek)
• An antifungal medication such as clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Nizoral) or voriconazole (Vfend)
• An antidepressant such as nefazodone
• Heart or blood pressure medication
• HIV/AIDS medication, such as amprenavir (Agenerase), atazanavir (Reyataz), darunavir (Prezista), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase, Fortovase) or ritonavir (Norvir)
• Seizure medication such as carbamazepine (Tegretol), phenobarbital (Luminal), or phenytoin (Dilantin)

This list is not complete and there may be other drugs that can interact with this medication. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

If you experience any of the following serious side effects, stop taking Tadalis SX (Tadalafil), refrain from sexual activity and seek emergency medical attention or contact your doctor immediately:

• An allergic reaction (difficulty breathing, closing of the throat, swelling of the lips, tongue or face, hives)
• Chest pain or irregular heartbeat
• Dizziness, nausea, or angina (pain, tightness, discomfort, numbness, or tingling in the chest, arms, neck or jaw)
• Swelling of the ankles or legs
• Shortness of breath
• Prolonged or severe dizziness
• A prolonged (lasting longer than 4 hours) or painful erection

 Other, less serious side effects may be more likely to occur. Continue to take Tadalis SX (Tadalafil) and talk to your doctor if you experience:

• Headache
• Indigestion
• Back pain
• Muscle aches
• Flushing
• Stuffy or runny nose
• Temporary blue tint in vision or difficulty telling the difference between the colors blue and green (uncommon)

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.