Generico Atopica

Precautions

• Any allergies
• Any vaccinations
• A history of chickenpox or shingles
• Uncontrolled high blood pressure
• Cancer
• Skin lesions of unknown cause
• Current use of radiation therapy (including phototherapy with PUVA or UVB)
• Kidney or liver diseases
• Any recent or current infections
• Seizures
• Untreated mineral imbalance (e.g. low magnesium or high potassium)
• Blood disorders
• Diabetes
• High cholesterol

Cyclosporine is classed as FDA Pregnancy Category C, which means it is not yet known if it can be harmful to an unborn baby. Inform your doctor immediately if you are pregnant or become pregnant during treatment with Cyclosporine.
Do not use this medication while breastfeeding. Cyclosporine may pass into breast milk and could potentially harm a nursing infant. If you are breastfeeding and want to start treatment with Cyclosporine, contact your doctor immediately.

Cyclosporine may reduce the levels of magnesium in the blood stream. You should talk to your doctor about adding more magnesium to your diet.

Using Cyclosporine may cause swelling and growth of the gums (gingival hyperplasia). Brush your teeth and floss daily to minimize this problem and visit your dentist regularly.

Cyclosporine reduces the actions of your immune system and can therefore cause serious infections. Make sure you maintain a good personal hygiene while taking Cyclosporine.

Patients who take immunosuppressive medication in the long term are at increased risk of skin cancer. Avoid exposure to strong sunlight and wear a good sunscreen or protective clothing.

Drug Interactions

• Birth control pills
• Carvedilol
• Caspofungin
• Digoxin
• Etoposide
• Ezetimibe
• Other immunosuppressants (e.g. Azathioprine, Methotrexate, Sirolimus)
• Acyclovir, Aminoglycoside
• Antibiotics including Tobramycin, Amphotericin B, Colchicine
• Fibrates including Fenofibrate
• Melphalan
• NSAIDs including Diclofenac and Sulindac
• Ranitidine
• Sulfa drugs including Sulfamethoxazole
• Vancomycin
• Allopurinol, Amiodarone, Azole)
• Antifungals (including Fluconazole and Ketoconazole)
• Barbiturates including Phenobarbital, Bromocriptine
• Calcium channel blockers including Diltiazem, Nicardipine and Verapamil
• Cimetidine
• HIV protease inhibitors including Indinavir, Imatinib
• Macrolide antibiotics including Erythromycin
• Certain man-made male hormones such as Danazol and Methyltestosterone
• Methylprednisolone
• Metoclopramide
• Metronidazole
• Nafcillin
• Nefazodone
• Octreotide
• Quinupristin, Dalfopristin
• Rifamycins including Rifampin
• Certain anti-seizure drugs including Carbamazepine and Phenytoin
• St. Johns wort
• Ticlopidine
• Nifedipine
• Orlistat
• Certain Guinolones (Ciprofloxacin, Norfloxacin)
• Repaglinide
• Other statins (Atorvastatin)
• Sulfinpyrazone
• Temsirolimus
• Terbinafine
• Tolterodine
• Drugs that may increase potassium levels (e.g. ACE inhibitors including Lisinopril, ARBs including Losartan, potassium supplements, diuretics including Amiloride and Spironolactone

The above is only a partial list and other medications may interact with Cyclosporine. Inform your doctor of all other prescription and over-the-counter medicines you use, including vitamins, nutritional supplements, herbal pills and medication prescribed by another doctor. Do not change medications without talking to your doctor first.

When taking Cyclosporine, you may notice any of the following common side effects:

• Tremors or shaking
• Increased hair growth
• Headache or body pain
• Diarrhea, constipation, vomiting
• Numbness or tingly feeling
• Acne
• Swollen, red or painful gums
• Dizziness, flushing
• High blood pressure

Notify your doctor immediately if you experience any of these serious side effects:

• Urinating less than usual or not at all
• Drowsiness, confusion, mood changes, increased thirst
• Swelling, weight gain, feeling short of breath
• Blurred vision, headache or pain behind your eyes, sometimes with vomiting
• Seizure (convulsions)
• Muscle pain or weakness, fast heart rate, feeling light-headed
• Signs of infection such as fever, chills, sore throat, flu symptoms
• Pale skin, easy bruising or bleeding, unusual weakness
• Nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
• Fast or irregular heartbeat
• Unusual weight loss or gain
• Hearing problems
• Changes in the appearance of skin moles or lesions
• Swollen glands or unusual lumps

Seek immediate medical help if you experience any of the following signs of an allergic reaction to Cyclosporine:

• Hives
• Difficulty breathing
• Swelling of the lips, face, tongue or throat

This is only a partial list of possible side effects and others may occur. Contact your healthcare provider immediately if any other side effects occur than the ones listed above or if they are especially bothersome.